Figure 1
The alum alone treatment inhibits H22 tumor growth.
Groups of female Balb/c mice (seven per group) were inoculated s.c. with 105 per mouse of H22 tumor cells on day 0. Tumor-bearing mice were injected i.p. with 0.25 mg/250ul Al(OH)3 or 250 ul PBS, twice weekly for 3 consecutive weeks. (A) A schematic representation of treatment protocol. (B) Line graph depicting the tumor volume in H22 tumor-bearing mice receiving different treatments over time. (C) Tumor volume changes in H22 tumor-bearing mice treated with Al(OH)3 or PBS starting on the 5th day. (D) Photos of tumors from mice sacrificed and solid tumors isolated on day 22. (E) Kaplan-Meier survival analysis of each group. Each value represents mean ± SEM. *p < 0.05, **p < 0.01 and ****p < 0.0001. Unmarked comparisons are not statistically significant.
