Table 1 Summary of SNV analysis in spermatozoal samples across different categories of the patients.

From: Copy number variation and microdeletions of the Y chromosome linked genes and loci across different categories of Indian infertile males

S. No.

SNV type

Patients (%) with allele A + B

Patients (%) with allele A only

Mutations observed in RS

Patients (%) with allele B only

Mutations observed in RS

OS

AZ

INS

NFM

OS

AZ

INS

NFM

OS

AZ

INS

NFM

1

DAZ-SNV_I

100

100

100

100

–

–

–

–

None

–

–

–

–

None

2

DAZ-SNV_II

84

74

90

100

–

–

–

–

None

16

26

10

–

G > A (MboI)

3

DAZ-SNV_III (sY586)

84

74

90

100

–

–

–

–

None

16

26

10

–

T > C (TaqI)

4

DAZ-SNV_IV

84

74

90

100

–

–

–

–

None

16

26

10

–

T > C (AluI)

5

DAZ-SNV_V (sY587)

74

39

55

100

–

–

–

–

None

26

61

45

–

T > C (DraI)

6

DAZ-SNV_VI

86

65

92

100

14

35

8

–

G > T (AflIII)

–

–

–

–

None

7

DAZ-SNV_VII (sY581)

100

100

100

100

–

–

–

–

None

–

–

–

–

None

8

BPY2

74

39

92

100

26

61

8

–

G > A (EcoRV)

–

–

–

–

None

  1. *OS, AZ, INS and NFM indicate oligospermic, azoospermic, infertile males with normal spermiogram and normal fertile males, respectively. RS means restriction site specific to a particular SNV, whereas “-”sign indicates absence of the allele. We used 55 control fertile males and all were found to be normal.
Back to article page