Figure 1

Disease-coverage profiles of the biomarkers.
664 (27 in clinical trial or use) non-invasive molecular biomarkers are colored in light (deep) red. 592 (69 in clinical trial or use) non-invasive molecular biomarkers are colored in light (deep) green. The 94 (13 in clinical trial or use and 73 FDA endorsed apps) physiological and conventional biomarkers are colored in light (deep) blue. Each leaf in the tree represents a specific ICD code as follows: A00-B99: infectious and parasitic diseases, C00-D49: Neoplasms, D50-D89: Diseases of the blood and related organ and immune disorders, E00-E89: Endocrine, nutritional and metabolic diseases, F01-F99: Mental, Behavioral and Neurodevelopmental disorders, G00-G99: nervous system disorders, H00-H59: eye and adnexa diseases, H60-H95: Diseases of the ear and mastoid process, I00-I99: circulatory system disorders, J00-J99: respiratory system disorders, K00-K95: digestive system disorders, L00-L99: skin and subcutaneous tissue disorders, M00-M99: musculoskeletal system and connective tissue disorders, N00-N99: genitourinary system disorders, O00-O9A: Pregnancy, childbirth and the puerperium, P00-P96: conditions originating in the perinatal period, Q00-Q99: Congenital malformations, deformations and chromosomal abnormalities, R00-R99: conditions not elsewhere classified, S00-T88: Injury, poisoning and certain other consequences of external causes, V00-Y99: External causes of morbidity, Z00-Z99: Factors influencing health status and contact with health services