Figure 5 | Scientific Reports

Figure 5

From: CD147 monoclonal antibody mediated by chitosan nanoparticles loaded with α-hederin enhances antineoplastic activity and cellular uptake in liver cancer cells

Figure 5

In vitro cytotoxicity of different formulations.

(A) Cytotoxic effect of void CS-CD147-NPs on HepG2 and SMMC-7721 cells after incubation for 24 h (n = 3); (B) cytotoxic effect of α-Hed, α-Hed-CS-NPs and α-Hed-CS-CD147-NPs on HepG2 cell line after incubation for 24 h (n = 3); (C) cytotoxic effect of α-Hed, α-Hed-CS-NPs and α-Hed-CS-CD147-NPs on SMMC-7721 cell line after treatment for 24 h (n = 3); and (D) cytotoxic effect of various formulations containing α-Hed on HSC cell line after incubation for 24 h (n = 3). *p < 0.05, **p < 0.01 versus α-Hed-CS-NPs.

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