Figure 4

Exo-metabolome analysis of HoxBan mono- and coculture spent medium.
(a) Hierarchical clustering analysis (HCA) of the top 25 metabolites ranked by the Anova Test. (b) Principle component analysis of the metabolites in the medium after 18 h culture. PC1 differentiates between cultures with or without F. prausnitzii. PC2 differentiates between F. prausnitzii monocultures and the two Caco-2- F. prausnitzii cocultures.