Figure 2
From: DNA methylation is stable during replication and cell cycle arrest
Global methylation is consistent after replication and cell cycle arrest.
(A) Mean methylation for each cell cycle phase from each donor profiled. (B) Distribution of high-frequency smoothed methylation values from CpGs with sufficient coverage from whole genome bisulfite sequencing (WGBS) for each donor profiled. (C) Distribution of high-frequency smoothed methylation values from all CpGs analyzed for each donor and cell cycle phase analyzed. Outliers have been removed for plotting. (D) Distribution of mean high-frequency smoothed methylation values across all donors from CpGs within and outside the regions previously identified as hypomethylated blocks in colon cancer for each phase profiled. Outliers have been removed for plotting.
