Figure 2
From: TRAIL-R2 Superoligomerization Induced by Human Monoclonal Agonistic Antibody KMTR2
Dimeric structure of an ecTRAIL-R2/KMTR2-Fab complex rendered by crystallographic two-fold symmetry.
The heavy and light chains of neighboring molecules rendered by crystallographic symmetry are colored purple and brown, respectively. (a) Overall structure. Dashed lines and ellipse indicate the two-fold axis. (b) Close-up view of the interface between two KMTR2-Fab molecules (stereo representation). Residues related to the interaction between two KMTR2-Fab molecules are represented by a stick model. The subscript “S” in label means “symmetry” molecule.
