Figure 2
From: Anti-sense DNA d(GGCCCC)n expansions in C9ORF72 form i-motifs and protonated hairpins
Coexistence of i-motifs and protonated hairpins.
(a) Imino region of 1H NMR spectra of d(G2C4)4 at 5 °C and pH 4.7, 6.0 and 7.2. (b) Imino region of 1H NMR spectra of d(G2C4)4 at 5, 25 and 37 °C at pH 4.7. The vertical scale of the spectral region indicated by the dotted box has been enlarged three-fold. (c) Imino region of 1H NMR spectra of d(G2C4)8 at 5 °C and pH 4.7, 6.0 and 7.2. (d) Imino region of 1H NMR spectra of d(G2C4)8 at 5, 25 and 37 °C at pH 4.7. The vertical scale of the spectral region indicated by the dotted box has been enlarged three-fold.
