Table 2 Newly identified loci associated with WC/WHR variation in East Asian-ancestry populations, by gender.
Nearby gene | Chr | SNP | Alleles | Among men | Among women | Test for homogeneity | ||||
|---|---|---|---|---|---|---|---|---|---|---|
Number | β(SE) | P | Number | β(SE) | P | P | ||||
WCadjBMI | ||||||||||
EFEMP1 | 2 | rs3791679 | A/G | 21172 | 4.04(0.63) | 1.76E-10 | 42605 | 2.43(0.49) | 6.31E-07 | 4.37E-02 |
ADAMTSL3 | 15 | rs8030379 | A/G | 16135 | 1.41(0.72) | 4.89E-02 | 33848 | 2.37(0.52) | 5.70E-06 | 2.80E-01 |
CNPY | 12 | rs3809128 | C/T | 11098 | 2.08(1.07) | 5.15E-02 | 18575 | 1.59(0.88) | 7.30E-02 | 7.24E-01 |
GNAS | 20 | rs2057291 | G/A | 11626 | 3.10(1.01) | 2.15E-03 | 26302 | 1.99(0.60) | 8.70E-04 | 3.44E-01 |
WHRadjBMI | ||||||||||
NID2 | 14 | rs1982963 | A/G | 17516 | 2.88(1.04) | 5.37E-03 | 33264 | 6.26(0.78) | 8.88E-16 | 9.32E-03 |
HLA-DRB5 | 6 | rs5020946 | T/G | 14055 | 3.17(0.97) | 1.10E-03 | 30049 | 3.57(0.65) | 3.54E-08 | 7.32E-01 |
WCnoBMI | ||||||||||
CEP120 | 5 | rs10051787 | T/C | 20191 | 4.60(1.00) | 4.15E-06 | 40033 | 3.82(0.70) | 4.89E-08 | 5.27E-01 |
TSC22D2 | 3 | rs1868673 | C/A | 10742 | 5.58(1.54) | 2.93E-04 | 24820 | 4.28(0.91) | 2.40E-06 | 4.67E-01 |
SLC22A2 | 6 | rs368123 | G/A | 21164 | 2.30(0.97) | 1.73E-02 | 40581 | 3.64(0.70) | 1.91E-07 | 2.61E-01 |
