Table 1 Characteristic of studies included in the meta-analysis.

From: Association between cadmium exposure and renal cancer risk: a meta-analysis of observational studies

Study

Year

Country

Study design

No. of patients

No. of subjects

Sex

Age,Median(Range),yrs

Exposure type

Study period

Adjustment for covariates

Kolonel LN

1976

United States

A case-control study

64

333

M

NA(50-79)

Occupational exposure

1957-1964

Unadjust

Armstrong BG

1985

Britain

A nested case-control study

9

36

W and M

NA(NA)

Occupational exposure

NA

Unadjust

Partanen T

1991

Finland

A case-control study

408

1227

W and M

63(26–95)

Occupational exposure

1977–1978

Unadjust

McCredie M

1993

United States

A population based case-control study

489

1012

W and M

NA(20–79)

Occupational exposure

1989–1991

Adjusted for age, sex, method of interview and education.

Mandel JS

1995

Mixed countres (Austrial,Denmark,Germany,Sweden and United States)

A multicenter collaborative case-control study

1732

4041

W and M

NA(5–68+)

Occupational exposure

1961–1979

Adjusted for age, smoking status, heating oils, kerosene, diesel fuel. body-mass index, education and study center.

PeschB

2000

German and British

A case-control study

935

5233

W and M

NA(40-80+)

Occupational exposure

1991–1995

Adjusted for age, study centre and smoking.

Hu J

2002

Canada

A case-control study

1279

6649

W and M

NA(20–70+)

Occupational exposure

1994–1997

Adjusted for 10 year age groups, province, education,BMI(<20, 20-27, >27), pack-years of smoking, alcohol use and total comsuption of meat

Boffetta P

2011

Europe

A hospital-based case-control study

1097

2573

W and M

NA(45–65+)

Occupational exposure

1993–2003

Adjusted for gender, age (5-year categories), study centre and known or suspected risk factors of RCC: place of residence (r ural/urban), tobacco smoking (non-smokers, ex-smokers and cur rent smokers of 1 e19, 20e 39 and 40 or more pack-years), body mass index (calculated as weight/height 2 and classi fied in five cate-gories: less than 25, 25e 27.4, 27.5 e29.9, 30e 34.9 and 35 or more kg/m 2) and self-reported histor y of hypertension.

Garcia-Esqinas E

2014

United States

A prospective cohort study

25

3792

W and M

56.2 (45–74)

Non-polluted exposure

1989–1991

Adjusted for sex, age, smoking status (never, former, current), cigarette pack-years (continuous) and BMI (<25, 25–30, ≥30 kg/m2).

  1. NA, not available; M, male; W, female.