Figure 4 | Scientific Reports

Figure 4

From: CellMethy: Identification of a focal concordantly methylated pattern of CpGs revealed wide differences between normal and cancer tissues

Figure 4

Divergence and specificity of CM.

(A) Standard deviations of each tissue from average value of all normal tissues/cells. Blue represents the standard deviations of methylation levels. Red represents the standard deviations of CM fractions. (B) Differential degree between normal and cancer cells in promoter, 5′-UTR, exon, intron, 3′-UTR, DHS, CGI and CGS regions. Dark red represents the differential degree of CM fractions, while light red represents the differential degree of methylation levels. (C) Distribution of the number of samples that shared the same CM or methylation regions. Blue represents CMRs with methylation levels greater than 0 and red represents a CM fraction greater than 0. (D) Distribution of CMRs (%) among somatic tissues. Normal represents all normal tissues/cells; others represent each cancer.

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