Table 4 Crude and adjusted odds ratios (ORs) and 95% confidence intervals (CIs) for acute appendicitis of sampled patients by gastric ulcer, duodenal ulcer, H. pylori-associated peptic ulcer and NSAIDs-associated peptic ulcer.

From: Acute Appendicitis Is Associated with Peptic Ulcers: A Population-based Study

Outcomes

Patients with acute appendicitis n = 3574

Controls n = 3574

No.

%

No.

%

Presence of prior gastric ulcer

464

13.0

354

9.9

Odds ratio (95% CI)

1.36*** (1.17~1.57)

1.00

Adjusted OR (95% CI)

1.41*** (1.22~1.64)

1.00

Presence of prior duodenal ulcer

256

7.2

210

5.9

Odds ratio (95% CI)

1.24* (1.02~1.49)

1.00

Adjusted OR (95% CI)

1.27* (1.05~1.54)

1.00

Presence of prior H. pylori-associated peptic ulcer

449

12.6

305

8.5

Odds ratio (95% CI)

1.54*** (1.32~1.80)

1.00

Adjusted OR (95% CI)

1.59*** (1.36~1.86)

1.00

Presence of prior NSAIDs-associated peptic ulcer

255

7.1

128

3.6

Odds ratio (95% CI)

2.07*** (1.66~2.57)

1.00

Adjusted OR (95% CI)

2.18*** (1.75~2.72)

1.00

  1. The adjusted OR was calculated by a conditional logistic regression which was adjusted for hypertension and diabetes.
  2. ***p < 0.001, **p < 0.01, *p < 0.05.