Table 2 Proteomic profiling in urine among post-exposure office workers (115/114), pre-exposure welding workers (116/114) and post-exposure welding workers (117/114) using iTRAQ coupled with LC-MS/MS.

From: Urinary neutrophil gelatinase-associated lipocalin is associated with heavy metal exposure in welding workers

Accession no.

Protein description

Protein score

MW (kDa)

Sequence covered (%)

Protein PI

Office workers (post-exposure)

Welding workers (pre-exposure)

Welding workers (post-exposure)

115/114

116/114

117/114

A1AG1

Alpha-1-acid glycoprotein 1

44

25842

7.5

4.93

1.366

1.431

1.160

ALBU

Serum albumin

3812

79721

47.8

5.92

1.376

1.190

1.264

AMBP

Protein AMBP

1305

42448

36.4

5.95

0.706

1.254

0.953

APOD

Apolipoprotein D

60

23221

10.1

5.06

1.116

0.872

0.775

CD44

CD44 antigen

80

84927

1.1

5.13

1.226

0.812

1.117

CD59

CD59 glycoprotein

179

15826

6.3

6.02

0.866

0.938

1.512

CO1A1

Collagen alpha-1(I) chain

55

148042

1.2

5.6

0.838

1.043

3.034

CO1A2

Collagen alpha-2(I) chain

58

136999

1.1

9.08

0.661

0.801

0.787

FLNA

Filamin-A OS = Homo sapiens

66

305972

0.3

5.7

0.825

0.923

1.380

IGHG2

Ig gamma-2 chain C region

101

39986

2.5

7.66

1.127

1.184

1.864

IGKC

Ig kappa chain C region

940

13037

80.2

5.58

0.825

1.658

1.443

KNG1

Kininogen-1

161

80279

8.5

6.34

1.389

0.739

1.155

LAC2

Ig lambda-2 chain C regions

325

12721

67

6.92

1.105

2.308

2.177

OSTP

Osteopontin

37

38421

5.1

4.37

0.964

0.428

0.761

P3IP1

Phosphoinositide-3-kinase-interacting protein 1

101

30039

4.2

4.92

1.054

0.762

0.375

PGBM

Basement membrane-specific heparan sulfate proteoglycan core protein

76

487121

0.5

6.06

0.922

1.824

1.375

PIGR

Polymeric immunoglobulin receptor

105

90394

4.7

5.58

1.183

0.933

1.609

PTGDS

Prostaglandin-H2 D-isomerase

601

22784

24.2

7.66

1.194

2.196

2.159

RNAS1

Ribonuclease pancreatic

50

19442

20.5

9.1

—

1.453

—

RRP12

RRP12-like protein

43

158739

0.5

8.97

1.509

0.952

3.702

SCG1

Secretogranin-1

107

85238

4.1

5.02

0.549

0.491

0.925

UROM

Uromodulin

2777

74372

22.7

5.05

0.87

0.438

0.559

YIPF3

Protein YIPF3

196

39703

2.9

5.47

0.927

0.793

1.754

ZA2G

Zinc-alpha-2-glycoprotein

48

37447

7.7

5.71

1.203

1.340

1.806

  1. – Not available. The iTRAQ ratios were obtained by the intensity of 115/114, 116/114 and 117/114 and the protein ratios contributed by at least two peptide ratios.
Back to article page