Figure 4 | Scientific Reports

Figure 4

From: Discovery of novel INK4C small-molecule inhibitors to promote human and murine hematopoietic stem cell ex vivo expansion

Figure 4

Confirmation of p18SMIs promoting expansion of human hematopoietic stem cells ex vivo.

(A) Experimental design. (B) Dose response assay assessing the effective concentrations of various p18SMIs (from primary screening hits) for their ability to promote proliferation of human HSCs. Data is mean ± SEM for all experiments of two or more and were performed in duplicate or triplicate. (***p < 0.001, **p < 0.01, *p < 0.05).

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