Table 3 Meta-analysis of the association between OLR1 rs11053646 and PCSK9 rs505151 with ischemic stroke.
From: The Influence of OLR1 and PCSK9 Gene Polymorphisms on Ischemic Stroke: Evidence from a Meta-Analysis
Variables | No. of study | Sample size (cases/controls) | Homozygous | Heterozygous | Recessive | Dominant | Co-dominant | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
OR (95% CI) | P | P het | I2 (%) | OR (95% CI) | P | P het | I2 (%) | OR (95% CI) | P | P het | I2 (%) | OR (95% CI) | P | P het | I2 (%) | OR (95% CI) | P | P het | I2 (%) | |||
OLR1 rs11053646 G > C | 4 | 1138/1213 | CC vs. GG | GC vs. GG | CC vs. (GG + GC) | (GC + CC) vs. GG | C vs. G | |||||||||||||||
1.00 (0.47–2.12) | 1.00 | 0.009 | 74 | 1.16 (0.83–1.62) | 0.39 | 0.01 | 74 | 1.00 (0.47–2.11) | 1.00 | 0.009 | 74 | 1.33 (1.11–1.58) | 0.002 | 0.45 | 0 | 1.24 (1.02–1.51) | 0.003 | 0.11 | 51 | |||
PCSK9 rs505151 A > G | 3 | 759/906 | GG vs. AA | AG vs. AA | GG vs. (AA + AG) | (AG + GG) vs. AA | G vs. A | |||||||||||||||
3.56 (0.96–13.20) | 0.06 | 0.68 | 0 | 1.19 (0.86–1.66) | 0.30 | 0.20 | 35 | 1.61 (0.04–67.16) | 0.06 | 0.68 | 0 | 1.29 (0.94–1.79) | 0.12 | 0.13 | 47 | 1.36 (1.01–1.85) | 0.05 | 0.09 | 54 | |||
