Figure 3
From: The TLR2 is activated by sporozoites and suppresses intrahepatic rodent malaria parasite development
P. yoelii sporozoite lysate induced peritoneal macrophages to release proinflammatory cytokines in a TLR2-dependent manner.
Peritoneal macrophages collected from WT, TLR2−/− or TLR4−/− mice were stimulated with or without SPZ lysate, FSL-1, LPS or NSG lysate. 17 h later, the concentration of IL-6, MCP-1 and TNF-α in the supernatant was determined using CAB beads. The experiment was repeated three times and all data were presented as the mean ± SD, *p < 0.05.
