Figure 6
From: Annexin A1 Deficiency does not Affect Myofiber Repair but Delays Regeneration of Injured Muscles
Anx A1 deficiency increases area of unregenerated regions in the vicinity of the injury site observed 5 days post injury.
(A) Images of the sections taken from w.t. and Anx A1−/− mice 5 days after notexin injection and labeled as in Fig. 5. Yellow lines show the borders of unregenerated (necrotic) regions (marked by *). Scale bar 50 μm. (B) Unregenerated (necrotic) regions were identified in muscle sections taken from w.t. and Anx A1−/− mice 5 or 7 days after notexin injection (n = 4 for w.t. mice at 7 day post-injury and n = 5 for all other conditions). We normalized the total unregenerated area in each analyzed field of view to the area of the muscle section in this field and present the means for each mouse in a given condition with a line within the group of the points to show the mean of the means for all mice in a given condition. Level of statistical significance of differences between w.t. and Anx A1-deficient mice is shown as * for p ≤ 0.05 and the rest of the samples were not significantly different from each other, p > 0.05.
