Figure 1
Schematic illustration and DLS readout showing (i) Conjugation of ssDNA Seq A and Seq B respectively to AuNPs, exhibiting a single peak/population on DLS (ii) ERE-containing AuNP dimer formation, which also showed a single peak a at ~10 nm right-shift compared to the conjugates (iii) Addition of ERβ to the as prepared ERE-containing AuNP dimer sensing probes and the presentation of a two-peak readout with an additional complex peak at around 200 nm. Observations of TEM images showed AuNP size and distributions generally corresponded to the DLS hydrodynamic diameter readouts.
