Figure 4

(A) AC Dimers consisting of 11 nm AuNPs joined by dsDNA containing mutated ERE sequence was fabricated and tested with 10 nM ERβ. Complex peak was observed, but at a low intensity relative to the dimer peak (B) ERE-containing AuNP dimers were queried with a non-specific protein – BSA. No complex peak was observed. All results were taken at 30 minutes after incubation with protein.