Figure 1 | Scientific Reports

Figure 1

From: The effect of androgens on ovarian follicle maturation: Dihydrotestosterone suppress FSH-stimulated granulosa cell proliferation by upregulating PPARγ-dependent PTEN expression.

Figure 1

Body weight and food intake in androgenized rats.

Female SD rats were randomly divided into three experimental groups (control, DHT and DHEA) and subcutaneously implanted with 90-day continuous-release pellets containing 7.5 mg DHT (daily dose, 83 μg), 200 mg DHEA (daily dose, 2.2 mg), or 7.5 mg placebo. The data are shown as means ± SD. (A) Weekly body weight per rat. Numbers of rats = 22, 19 and 21 for the DHT, DHEA and placebo groups, respectively. (B) Weekly food intake amount per rat. Number of rats = 9 in each group. In both (A,B), the levels of the DHT group were significantly higher than those of the other 2 groups, as determined by repeated measures ANOVA. *P < 0.05.

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