Figure 1
From: Characterization of Social Behaviors in caspase-3 deficient mice
Both Casp3−/− male and female mice exhibit hyperactivity in novel open field.
Graphs show (A) total ambulatory locomotion (p = 0.004 for main genotype effect, p = 0.6220 for main sex effect, p = 0.8865 for genotype × sex, by two-way ANOVA); (B) total fine activity (p = 0.01 for genotype, p = 0.372 for sex, p = 0.3261 for genotype × sex, by two-way ANOVA); (C) total rearing (p = 0.3775 for genotype, p = 0.0006 for sex, p = 0.4874 for genotype × sex, by two-way ANOVA) in novel open-field during 1 h; (D) percent of locomotor activity occurring in center portion of open field during 1 h test (p = 0.2069 for genotype, p = 0.4713 for sex, p = 0.1191 for genotype × sex, by two-way ANOVA). Bar graphs show mean ± SEM for 20 WT males, 20 Casp3−/− males, 20 WT females and 19 Casp3−/− females. *p < 0.05 for genotype effect within each sex, by Bonferroni post-hoc tests following two-way ANOVA with the factors of genotype and sex.
