Table 1 Median (IQR) of various parameters for control and NIDDM subjects with and without retinopathy.

From: Telomere mean length in patients with diabetic retinopathy

Parametrs

Control (n = 36)

NDR (n = 27)

NPDR (n = 45)

PDR (n = 13)

Age (yrs)

45 (38.5–51.75)

52 (46–63)

55 (46.5–60.5)

51.50 (45.50–58.75)

Hb

12.48 (11.40 13.73)

12.7(11.2–14.4)

13.2 (11.45–14.30)

12.05 (11.13–13.75)0.712*, 0.009**

HbA1c

4.80 (4.3–5.2)

6.72 (6.29 8.15)

6.90 (6.38–7.55)

6.95 (6.38–7.58) −695*, 0.012**

FBS

92.25 (83.52–97.9)

148.2 (129–189)

149.8 (110.75–184.75)

137.05 (95.64–177.22)

TC

165.5 (151–187.5)

175 (129.4–205)

174.6 (143.4–192.22)

166.55 (128.8–247.72)

TG

139.5(100–155.5)

112(80.2–138.2)

101.6 (80.29–152.6)

121.05 (85.52–195.25)

HDL

42.15 (38.35–46) 0.353*, 0.035**

45 (35.6–52)

45.3 (39.35–55.38)

40.62 (38.16–48.71)

LDL

91.8 (86.3–109.5)

108 (67.84–132.6)

95.9 (74.16–120.56)

94.69 (69.81–157.86)

VLDL

27.9 (20–31.1)

22.40 (16.04–27.64)

20.32 (16.06–30.52)

24.21 (17.10–39.05)

BUN

10 (9.65–12)

17 (13–20)

18 (14–24.5)

22.50 (18–42.50)

Creatinine

0.96 (0.89–1.07)

0.94 (0.80–1.11)

1.17 (94–1.32)

1.04 (0.95–1.55)

TP

7.15 (6.65–7.3)

7.3 (6.68–7.58)

7.3 (6.96–7.70)

7.16 (6.77–7.63)

FI

10.12 (9.17–12.93)

9.87 (7.49–12.49) 0.423*, 0.028**

12.62 (9.17–19.24)

12.82(9.73–16.19)

IR

2.47 (2.01–3.41)

3.55 (2.71–6.53)

4.18 (2.74–7.7)

4.77 (2.29–6.55)

SBP

120 (116–130)

130 (120–150)

140 (120–155)

135 (110–143.75)

DBP

80 (75–90)

90 (80–90)

90 (80–90)

82.5 (75–90)

  1. Data are median (interquartile range), Correlation coefficients (*) and p value (**) of telomere length with classical risk factors in control subjects and NIDDM subjects with and without retinopathy.
  2. TML in relation to Hb (r = 0.712, p = 0.009) and HbA1c (r = −0.695, p = 0.012) in the PDR subjects, HDL (r = 0.353, p = 0.035) in control subjects, FI (r = 0.423, p = 0.028) in NDR subjects.
  3. Haemoglobin (Hb), Glycosylated Hemoglobin type A1C (HbA1c), Fasting blood sugar (FBS), Total cholestrol (TC), Triglyceride (TG), High density lipoprotein (HDL), Low density lipoprotein (LDL),Very low density lipo protein (VLDL), Blood urea Nitrogen (BUN), Total Protein (TP), Fasting Insulin (FI), Insulin Resistance (IR), systolic blood pressure (SBP), Diastolic blood pressure (DBP).