Table 5 Potential associations seen in the entire cohort.
From: Are Immune Modulating Single Nucleotide Polymorphisms Associated with Necrotizing Enterocolitis?
SNP | Outcome | Genotype | Outcome | OR | p-value | 95% CI | ||
|---|---|---|---|---|---|---|---|---|
No | Yes | |||||||
IL-6 (rs1800795) | NEC | GG | 93 | 25 | 1.00 | |||
CG/CC | 40 | 40 | 1.74 | 0.11 | 0.88– 3.42 | |||
IL-6 (rs1800795) | Overall mortality | GG | 109 | 13 | 1.00 | |||
CG/CC | 50 | 9 | 2.54 | 0.08 | 0.90–7.23 | |||
TGFβ-1 (rs2241712) | Overall mortality | AA | 66 | 5 | 1.00 | |||
AG/GG | 92 | 18 | 2.99 | 0.049 | 1.01–8.86 | |||
TGFβ-1 (rs2241712) | NEC perforation | AA | 12 | 12 | 1.00 | |||
AG/GG | 28 | 13 | 0.28 | 0.044 | 0.08–0.97 | |||
TRIM21 (rs660) | NEC perforation | TT | 16 | 4 | 1.00 | |||
CT/CC | 16 | 15 | 4.64 | 0.038 | 1.09–19.78 | |||
SNP | Outcome | Genotype | Severity level | OR | p-value | 95% CI | ||
0 | 2 | 3 | ||||||
IL-6 (rs1800795) | NEC severity | GG | 83 | 14 | 26 | 1.00 | ||
CG/CC | 34 | 8 | 17 | 2.06 | 0.054 | 0.98–4.13 | ||
