Figure 1 | Scientific Reports

Figure 1

From: An engineered scorpion toxin analogue with improved Kv1.3 selectivity displays reduced conformational flexibility

Figure 1

Sequence comparison of Kv1.2- and Kv1.3-selective toxins.

The aligned primary sequences are shown for toxins for which the affinities for both Kv1.2 and Kv1.3 channels were determined. Toxins were classified as Kv1.2-selective, non-selective or Kv1.3-selective based on the ratio of the determined Kd values for the two channels. The positions of the two mutations (N17A and F32T) are indicated in the table in bold.

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