Figure 2 | Scientific Reports

Figure 2

From: Scaling-up Fermentation of Pichia pastoris to demonstration-scale using new methanol-feeding strategy and increased air pressure instead of pure oxygen supplement

Figure 2

Time-course profiles of the biomass-stat fed-batch HCDF at low (open diamond, v = 0.025 mL/g/h), middle (filled diamond, v = 0.035 mL/g/h) and high (open cycle, v = 0.050 mL/g/h) methanol feeding rates and under Ip-Air condition.

(a) Cell density profiles (DCW, g/L). (b) Volumetric enzyme activity profiles (U/L). (c) Biomass enzyme activity profiles (U/g). Data are means ± SD of three parallel measurements (*P < 0.05, **P < 0.01, ***P < 0.001). Note: the control was under Np-Ox condition with 10 mL/L/h methanol feeding.

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