Table 3 The association between rs2843710 SNP and severity of EV71 HFMD.

From: A functional polymorphism in IFNAR1 gene is associated with susceptibility and severity of HFMD with EV71 infection

SNP ID

Genotype

HD

M-EV71

S-EV71

M-EV71 Vs HD

S-EV71 Vs HD

S-EV71 Vs M-EV71

No (%)

No (%)

No (%)

P Value

OR (95% CI)

P Value

OR (95% CI)

P Value

OR (95% CI)

rs2843710

CC

251 (43.8)

310 (38.7)

132 (33.4)

0.0053

1.25(1.07–1.47)

< 0.0001

1.52(1.26–1.84)

0.0289

1.21(1.02–1.44)

 

CG

269 (46.9)

375 (46.8)

190 (48.1)

      
 

GG

53 (9.3)

116 (14.5)

73 (18.5)

      
  1. Note: Hardy-Weinberg equilibrium P values of rs2843710 were 0.11 in HD and were 0.88 in M-EV71 and were 0.75 in S-EV71. Abbreviations: HD, healthy donors; M-EV71, mild EV71 HFMD; S-EV71, severe EV71 HFMD; CI, confidence interval; OR, odds ratio.
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