Figure 2 | Scientific Reports

Figure 2

From: Variability of Action Potentials Within and Among Cardiac Cell Clusters Derived from Human Embryonic Stem Cells

Figure 2

Variability of action potentials within a single cardiac cell cluster and among different clusters.

(A) APD80 histogram of action potentials recorded from a cardiac cell cluster (cluster 9). Two peaks in the histogram indicate subpopulations with predominantly long or short durations. (B) Sample action potentials recorded from this cluster. Center: APD80 map, showing two distinct regions with long or short AP durations. (C–F) Single AP parameter histograms (APD80, APD30, triangulation and fractional repolarization; see main text for definition) of 32 cardiac cell clusters paced at 90 bpm. Each row represents one cluster. The overall distribution (bottom row) is the summation of all recording sites (n = 23117) from these 32 clusters.

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