Figure 5
From: Col4a1 mutations cause progressive retinal neovascular defects and retinopathy
Elevated expression levels of pro-angiogenic factors in retinas of Col4a1+/Δex41 mice.
We found significantly increased Vegfa (a) and Pdgfb expression (b) at P21 (Col4a1+/+: n = 17; Col4a1+/Δex41: n = 23) but not at P90 (n = 6 for both genotypes), while Pgf expression was significantly higher in Col4a1+/Δex41 retinas at both ages (c). We did not observe significant differences for Vegfb, Vegfc, Angpt1 and Angpt2 (d–f). Scatter plot with mean ± standard deviation; ***p < 0.05.
