Figure 6 | Scientific Reports

Figure 6

From: The temporal topography of the N-Methyl- N-nitrosourea induced photoreceptor degeneration in mouse retina

Figure 6

(A) Quantification of the photoreceptor-specific proteins levels by western blot analysis. It was found that the expression levels of both the rhodopsin and cone arrestin decreased progressively after P1. However, by the time points of P7, almost all of the rhodopsin extinguished, while a substantially proportion of cone arrestin was relatively preserved. (B) The rhodopsin loss was disproportioned to the cone opsin loss during the whole degeneration process: the cone arrestin loss was relatively milder than the rhodopsin loss respectively at P1, P3, (ANOVA analysis followed by post-hoc test, n = 10; *P < 0.05, **P < 0.01 for differences compared with controls; #P < 0.05, ##P < 0.01 for differences compared with previous time point group).

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