Table 1 Characteristics of included studies in the meta-analysis.

From: Tooth loss is associated with increased risk of esophageal cancer: evidence from a meta-analysis with dose-response analysis

References

Country

Study design

Sample sizes

Age (yrs)

Outcomes

Definition of reference group

Estimation (95%CI) (Highest vs. lowest)

Abnet 2001

China

Cohort

28868

57(12)*

ESCC

None lost tooth

0.90 (0.49–1.70)

Abnet 2005

Finland

Cohort

29124

57.2 ± 5.1#

ESCC

Lost ≤ 10 teeth

0.73 (0.35–1.55)

Dye 2007

China

CS

579

40–67

ESCC

Lost < 4 teeth

1.45 (0.76–2.76)

Guha 2007

Latin America

CC

173/1805

any age

ESCC

Lost ≤ 5 teeth

1.07 (0.41–2.77)

Guha 2007

Central Europe

CC

132/928

any age

ESCC

Lost ≤ 5 teeth

1.80 (1.80–4.07)

Michaud 2008

USA (White, Asian, Black)

Cohort

48375

40–75

EC

Lost ≤ 8 teeth

1.34 (0.78–2.30)

Abnet 2008

Iran

CC

283/560

65(56–73)/65(57–72)*

ESCC

Lost ≤ 12 teeth

1.79 (1.03–3.13)

Hiraki 2008

Japan

CC

354/708

20–79

EC

Lost ≤ 11 teeth

2.36 (1.17–4.75)

Dar 2013

India

CC

703/1664

61.6 ± 11.1/59.8 ± 11.1#

ESCC

None lost tooth

1.08 (0.68–1.69)

  1. CS, cross-sectional; CC, case-control; EC, esophageal cancer; ESCC, esophageal squamous cell carcinoma;*, median (IQR);#, mean ± standard deviation.