Figure 6 | Scientific Reports

Figure 6

From: Resistin, a fat-derived secretory factor, promotes metastasis of MDA-MB-231 human breast cancer cells through ERM activation

Figure 6

Ezrin is involved in resistin-induced vimentin expression

. (A) MDA-MB-231 cells were treated with resistin (25 ng/ml) and cultured for the indicated times. Cell lysates (30 μg) were analyzed by western blots using antibody against vimentin; β-actin was used as a control. (B) Cells transfected with either non-target or ezrin siRNA were treated with resistin (25 ng/ml) for 24 h. Vimentin, ezrin and β-actin were detected by western blots. (C) Schematic diagram of the mechanism of resistin.

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