Table 1 Proteins differentially expressed in OIL and 17β-estradiol female CCI D7 mice.

From: 17beta-estradiol counteracts neuropathic pain: a behavioural, immunohistochemical and proteomic investigation on sex-related differences in mice

Accession^a	Description (Gene Name)	Highly represented^b	OIL:17β-E ratio^c	Location^d	Type(s)^d
Q8VCM7	Fibrinogen gamma chain OS Mus musculus GN Fgg PE 2 SV 1	17β-estradiol*	0,1	Cytoplasm	other
P99029	Peroxiredoxin 5 mitochondrial OS Mus musculus GN Prdx5 PE 1 SV 2	17β-estradiol*	0,1	Plasma Membrane	other
Q9DCV7	Keratin type II cytoskeletal 7 OS Mus musculus GN Krt7 PE 1 SV 1	17β-estradiol*	0,1	Extracell Space	other
Q8CGP0	Histone H2B type 3 B OS Mus musculus GN Hist3h2bb PE 1 SV 3	17β-estradiol*	0,1	Extracell Space	other
P13541	Myosin 3 OS Mus musculus GN Myh3 PE 2 SV 2		0,23	Cytoplasm	transporter
P46660	Alpha internexin OS Mus musculus GN Ina PE 1 SV 2		0,31	Cytoplasm	other
P13542	Myosin 8 OS Mus musculus GN Myh8 PE 1 SV 2		0,38	Cytoplasm	other
P27573	Myelin protein P0 OS Mus musculus GN Mpz PE 1 SV 1		0,54	Cytoplasm	other
A2AQP0	Myosin 7B OS Mus musculus GN Myh7b PE 3 SV 1		0,57	Plasma Membrane	other
P07759	Serine protease inhibitor A3K OS Mus musculus GN Serpina3k PE 1 SV 2		0,64	Cytoplasm	enzyme
Q00623	Apolipoprotein A I OS Mus musculus GN Apoa1 PE 1 SV 2		0,67	Cytoplasm	other
P07724	Serum albumin OS Mus musculus GN Alb PE 1 SV 3		0,7	Extracell Space	other
Q5SX40	Myosin 1 OS Mus musculus GN Myh1 PE 1 SV 1		2,69	Cytoplasm	enzyme
Q91Z83	Myosin 7 OS Mus musculus GN Myh7 PE 1 SV 1		3,1	Extracell Space	transporter
P32848	Parvalbumin alpha OS Mus musculus GN Pvalb PE 1 SV 3	OIL^†	10	Cytoplasm	enzyme
P70296	Phosphatidylethanolamine binding protein 1 OS Mus musculus GN Pebp1 PE 1 SV 3	OIL^†	10	Extracell Space	other
P48036	Annexin A5 OS Mus musculus GN Anxa5 PE 1 SV 1	OIL^†	10	Cytoplasm	other
P06745	Glucose 6 phosphate isomerase OS Mus musculus GN Gpi PE 1 SV 4	OIL^†	10	unknown	other
P63101	14 3 3 protein zeta delta OS Mus musculus GN Ywhaz PE 1 SV 1	OIL^†	10	Extracell Space	other
O88990	Alpha actinin 3 OS Mus musculus GN Actn3 PE 2 SV 1	OIL^†	10	Extracell Space	transporter

Proteins upregulated (†) and downregulated (*) in OIL vs 17β-estradiol female CCI D7 nerves.
^aUnique protein sequence identifier according to UniProtKB/Swiss-Prot 2012-11, Rel. November 8, 2012, restricted to Mus Musculus Taxonomy.
^bProtein found highly represented in the indicated group. Highly represented proteins are those that in the Differential Proteomics Analysis have been detected in only one group (treated with OIL or 17β-estradiol in this case) and appeared in every injection for that group. In this work we associated to them an arbitrary ratio value equal to 10 fold or 0.1 fold.
^cRatio of expression between 2 experimental groups.
^dAccording to Ingenuity Pathways Analysis (Ingenuity® Systems, Build version 212183, Content version 1240262, Release date 2012/03/09, www.ingenuity.com).

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Table 1 Proteins differentially expressed in OIL and 17β-estradiol female CCI D7 mice.

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