Figure 1
From: Antitumor Activity of cGAMP via Stimulation of cGAS-cGAMP-STING-IRF3 Mediated Innate Immune Response
cGAMP Possesses Potent Anti-tumor Activity against Murine Colon 26 Adenocarcinoma.
Colon 26 tumor-bearing mice were treated with cGAMP from day 0 to day 20 with 5, 10 and 20 mg/kg, respectively. (A) Mean tumor volumes. (B) Survival rates of mice. (C) Tumor weights. Representative data are shown from three experiments conducted with 10 mice per group. Data are represented as mean ± SEM, *p < 0.05 and **p < 0.01 (Student’s t test in A and C and log rank [Mantel-Cox] test in B).
