Figure 5
From: Antitumor Activity of cGAMP via Stimulation of cGAS-cGAMP-STING-IRF3 Mediated Innate Immune Response
cGAMP Boosts the Expression of STING and IRF3 in Tumor Tissues.
Colon 26 tumor-bearing mice were treated with cGAMP from day 0 to day 20 with 20 mg/kg once a day. (A) STING (stimulator of interferon genes) and (B) IRF3 (IFN regulatory factor 3) were detected with immunofluorescence technique. Scale bar =200 μm.
