Figure 6 | Scientific Reports

Figure 6

From: Enhanced engraftment, proliferation and therapeutic potential in heart using optimized human iPSC-derived cardiomyocytes

Figure 6

Proliferation capacity of iPSC-CMs in vivo in infarcted mouse hearts.

(a) Comparison of Ki67 immunostaining of engrafted CMs at several time points: green, cTNT; red, Ki67; blue, Hoechst. Grafted areas are enclosed by white dotted lines. Scale bars: 100 μm. (b) Percentage of Ki67-positive CMs at several time points. Values are mean ± SD. *p < 0.05 by one-way ANOVA followed by Tukey’s posthoc test. (c) Schematic summary of the luminescence signal time course shown in Fig. 5a after direct injection of day20 CMs.

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