Figure 6 | Scientific Reports

Figure 6

From: Astragaloside IV inhibits microglia activation via glucocorticoid receptor mediated signaling pathway

Figure 6

ASI enhanced GR activity in cells.

(A) ASI increased GR-luciferase activity in HEK293 cells transfected with GR, the effect of which could be blocked by RU486. One-way ANOVA with Dunnett’s multiple comparison test was used for the statistics. *p < 0.05; **p < 0.01; ***p < 0.001 vs control group, N = 4/group, mean ± S.E.M. (B) ASI enhanced nuclear translocation of GR in BV-2 cells upon LPS stimulation. The data shown were one of the representative results from at least three independent experiments.

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