Figure 1
From: Endothelial cell dysfunction and cardiac hypertrophy in the STOX1 model of preeclampsia
Gene Set Enrichment Analysis (GSEA).
The gene expression data generated by RNA-seq was analyzed using GSEA to extract biological knowledge. Highly, significant enriched gene-sets are shown here. In every thumbnail, the green curve represents the evolution of the density of the genes identified in the RNA-seq. The False Discovery Rate (FDR) is calculated by comparing the actual data with 1000 Monte-Carlo simulations. The NES (Normalized Enrichment Score) computes the density of modified genes in the dataset with the random expectancies, normalized by the number of genes found in a given gene cluster, to take into account the size of the cluster.
