Figure 6
From: Irx3 is required for postnatal maturation of the mouse ventricular conduction system
In silico analysis identifies Nkx2.5, Tbx5 and Irx3 target genes.
(a–c) Venn diagrams showing the number of genes with ChIP-seq peaks, Irx motifs and protein encoding genes (PEG) for Nkx2.5 (a), Tbx5 (b) and Nkx2.5-Tbx5 (c). (d–f) Selected GO terms associated with biological process for Nkx2.5-Irx (d) Tbx5-Irx (e) and Nkx2.5-Tbx5-Irx (f) genes (for complete data set, see Supplemental Dataset). (g–h) Venn diagrams showing the overlap and distribution of Nkx2.5-Irx (green) & Tbx5-Irx genes (red), as well as Nkx2.5-Tbx5-Irx genes (yellow or blue) in comparison with VCS-enriched genes.
