Figure 3
From: Pterisolic Acid B is a Nrf2 Activator by Targeting C171 within Keap1-BTB Domain
SAR studies of J19 analogs as well as the preparation of positive and negative chemical probes.
(a) Structures of J19 and its analogs and Probes (b) N23 cells were treated with 4 μΜ of J19 and its analogues for 12 h and then subject to Luciferase assay. Error bars indicate the standard deviations from triplicate samples. (c) Western blot analysis after HKC cells treated by J19 and its analogues for 4.5 h using the indicated antibodies. (d) SAR studies of J19 analogs.
