Figure 1

Overall workflow for discovery (iTRAQ) and validation (MRM-ELISA) experiments.
TOF, tetralogy of Fallot; VSD, ventricular septal defects; PTA, persistent truncus arteriosus; MIX, a mixture of relatively rare types of CHDs; SCX, Strong Cation Exchange Chromatography; LC-ESI-MS-MS, Liquid chromatography electrospray ionisation tandem mass spectrometry.