Figure 1 | Scientific Reports

Figure 1

From: Geographic origin and evolutionary history of China’s two predominant HIV-1 circulating recombinant forms, CRF07_BC and CRF08_BC

Figure 1

Precise mapping of recombination breakpoints in the B’/C recombinant forms in western Yunnan.

Detailed subtype structure of the B’/C recombinant forms was estimated as described in Materials and Methods (see also Supplemental Figure S2, S3). Subtype B’ region (blue), subtype C region (magenta). The sites 1 through 8 are the recombination breakpoints shared among CRF07_BC, CRF08_BC and other B’/C recombinants that are indicated with thick vertical lines. Regions Ia (HXB2: 790–1191), Ib (HXB2: 1642–2010 nt) II (HXB2: 3330–5593 nt). IIIa (HXB2: 6541–7348 nt) and III (HXB2: 6541–8695) are the subtype C segments that were selected for the subregion MCC tree analyses (see Fig. 2) and temporal dynamic analyses of spatial diffusion for B’/C recombinants in order to examine the relationships and the timescale of emergence and diffusion of CRF07_BC/CRF08_BC.

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