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Figure 2

From: Geographic origin and evolutionary history of China’s two predominant HIV-1 circulating recombinant forms, CRF07_BC and CRF08_BC

Figure 2

MCC trees based on selected subtype C segments considering B’/C recombinant forms in this study.

Bayesian molecular clock analyses were performed using BEAST v1.74 (see methods for details) for different subtype C regions: (A) the concatenated gag region (Ia + Ib) (HXB2: 790–1191 nt and 1642–2010 nt), (B) the pol region (II) (3330–5593 nt) and (C) the env region (III) (6541–8695 nt).The tree branches are color-coded according to their respective genotypes and geographical locations. The medians of tMRCA are as follows: CRF07_BC ancestor = ~1994, CRF08_BC ancestor = ~1992, CRF57_BC ancestor = ~1993, CRF61_BC ancestor = ~2002, CRF62_BC ancestor = ~2003, CRF64_BC ancestor = ~1995, Yunnan RF ancestor = ~1987. Indian subtype C ancestor = ~1976 and African subtype C ancestor = ~1966 (see Table S1).

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