Figure 3

Estimated tMRCAs of subtype C and its recombinant lineages in China.
Estimated dates of the MRCA of CRF07_BC and CRF08_BC in comparison with nCRFs_BC and ancestors of URFs_BC were obtained for sub-genomic regions. Estimates were calculated under a GTR substitution model with a relaxed molecular clock and a Bayesian skyline plot coalescent model. Error bars represent the 95% higher probability density credible regions for each estimate. Estimates obtained using region (Ia + Ib:), (II) and (III) are labeled with square, triangle and diamond respectively.