Figure 8 | Scientific Reports

Figure 8

From: Downregulation of miR-522 suppresses proliferation and metastasis of non-small cell lung cancer cells by directly targeting DENN/MADD domain containing 2D

Figure 8

DENND2D is involved in miR-522 induced proliferation and metastasis of NSCLC cells.

(a) The effects of miR-522 and miR-mask in H460 cell viability was measured with an MTT assay. (b) The proliferation of H460cells was determined by EdU kit, assessed by fluorescence microscopy (200×). (c) Wound closure at 0 h and 24 h in H460 cells infected with miR-522 or miR-mask. Scale bar: 200 μm. (d) Transwell assays with Matrigel in H460 cells infected with miR-522 or miR-mask. Magnification: 100×. Scale bar: 200 μm. *P < 0.05 vs miR-control, #P < 0.05 vs miR-522.

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