Table 3 Correlation coefficients between bioconcentration and expression levels of all target genes.
Gene | Correlation coefficient | |||||
|---|---|---|---|---|---|---|
Brain | Liver | |||||
Racemate | (−)-PCB149 | (+)-PCB149 | Racemate | (−)-PCB149 | (+)-PCB149 | |
sod | 0.057 | −0.331 | −0.675** | −0.351 | −0.095 | −0.331 |
cat | −0.141 | −0.496** | −0.032 | −0.336 | 0.002 | −0.520** |
Gpx | 0.080 | −0.323 | −0.289 | −0.187 | −0.122 | −0.522** |
sdhaf2 | 0.378 | −0.394* | 0.088 | −0.217 | −0.042 | −0.454* |
ldha | −0.05 | −0.435* | −0.113 | 0.161 | 0.140 | −0.087 |
gapdh | 0.119 | −0.112 | 0.125 | −0.270 | −0.176 | −0.321 |
apoa1a | −0.231 | −0.319 | −0.016 | 0.004 | −0.087 | −0.330 |
alox5a | 0.543** | −0.002 | −0.147 | −0.038 | 0.152 | −0.513* |
alox12 | 0.394** | 0.082 | −0.1 | −0.210 | 0.016 | −0.178 |
comta | −0.021 | −0.500** | −0.05 | −0.351 | −0.041 | −0.362 |
hemk1 | 0.040 | −0.574** | −0.153 | −0.266 | −0.028 | −0.174 |
cyp2k6 | −0.313 | −0.217 | −0.736** | −0.340 | −0.036 | −0.239 |
cyp2aa4 | 0.639** | −0.006 | −0.267 | −0.226 | 0.070 | −0.502** |
cyp19a1b | −0.238 | −0.437* | 0.210 | −0.019 | 0.013 | −0.322 |
