Figure 1

Structures of S. aureus EF-G and FusB-type proteins.
(a) S. aureus EF-G (PDB ID 2XEX), annotated by domain and shown with fusidic acid (magenta sticks) modelled in the binding site through alignment with the structure of ribosome-bound, FA-bound EF-G from Thermus thermophilus (PDB ID 2WRI). (b) FusB-type proteins, FusB (PDB ID 4ADN, colored blue and red) and FusC (PDB ID 2YB5, colored green and yellow) annotated by domain. The coordinated zinc ion in the C-terminal domain is shown as a magenta sphere.