Table 8 Involvement of piwi protein in the inheritance of epimutations in DNMT3L expressing flies.

From: DNMT3L enables accumulation and inheritance of epimutations in transgenic Drosophila

Crosses

No. of larvae with tumors/ Total No. of Larvae (%)

Set 1

Set 2

Set 3

Average (%)

G5(Actin-3L) X G5(Actin-3L)

6/88(6.8)

7/96 (7.3)

5/87 (5.7)

6.6

G5 (Actin-3L) X piwi

0/103 (0)

0/103 (0)

0/106 (5)

0

piwi-Act-GAL4 X piwi-Act-GAL4; G1

0/116 (0)

0/107 (0)

0/102 (0)

0

  1. piwi – flies mutant for piwi protein (piwi06843/CyO; ry506/+); Actin-3L - DNMT3L expressing flies with Actin-GAL4 driver; piwi-Act-GAL4: DNMT3L expressing Actin-3L flies with mutant piwi gene.
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