Table 1 FCER1 genotypes in overall allergic rhinitis patients and control individuals.

From: A Nonsynonymous FCER1B SNP is Associated with Risk of Developing Allergic Rhinitis and with IgE Levels

 

Group

Non-mutated (frequency)

Heterozygous (frequency)

Homozygous (frequency)

Minor allele frequency

Comparison Allele frequency OR (95% C.I.); P; Pc

FCER1A

 rs2494262

Patients

0.266

0.476

0.258

0.496

0.93 (0.78–1.12); 0.411; 0.955

 

Controls

0.237

0.498

0.265

0.514

 

 rs2427837

Patients

0.563

0.371

0.066

0.251

0.95 (0.78–1.16); 0.814; 0.955

 

Controls

0.539

0.399

0.062

0.262

 

 rs2251746

Patients

0.553

0.379

0.068

0.257

1.00 (0.82–1.22); 0.872; 0.955

 

Controls

0.545

0.395

0.060

0.258

 

FCER1B

 rs1441586

Patients

0.279

0.501

0.220

0.471

1.03 (0.87–1.23); 0.500; 0.955

 

Controls

0.274

0.526

0.200

0.463

 

 rs569108

Patients

0.926

0.074

0.000

0.037

0.99 (0.62–1.57); 0.955; 0.955

 

Controls

0.925

0.075

0.000

0.037

 

 rs512555

Patients

0.928

0.072

0.000

0.036

0.99 (0.62–1.57); 0.936; 0.955

 

Controls

0.927

0.073

0.000

0.036

 

FCER1G

 rs11587213

Patients

0.718

0.262

0.019

0.150

0.96 (0.75–1.22); 0.898; 0.955

 

Controls

0.715

0.257

0.027

0.156

 

 rs2070901

Patients

0.526

0.384

0.089

0.282

0.94 (0.78–1.14); 0.732; 0.955

 

Controls

0.512

0.388

0.100

0.294

 

 rs11421

Patients

0.683

0.286

0.031

0.174

0.94 (0.75–1.17); 0.773; 0.955

 

Controls

0.679

0.274

0.047

0.184

 
  1. P values correspond to stratified Chi-Square Tests. Pc correspond values adjusted for multiple comparisons according the False Discovery Rate (FDR) procedure. OR: odds ratio. CI: 95% confidence interval.