Table 3 IgE values according to FCER1 genotypes.

From: A Nonsynonymous FCER1B SNP is Associated with Risk of Developing Allergic Rhinitis and with IgE Levels

 

Genotype

Allergic rhinitis alone

K-W Test across genotypes P; Pc

Allergic rinitis + Asthma

K-W Test across genotypes P; Pc

Overall patients

K-W Test across genotypes P; Pc

FCER1A

 rs2494262

C/C

184.94 ± 232.47

P = 0.139; Pc = 0.250

346.51 ± 482.83

P = 0.560; Pc = 0.937

294.33 ± 424.13

P = 0.935; Pc = 0.972

 

C/A

187.68 ± 188.84

267.86 ± 333.20

239.74 ± 293.54

 

A/A

266.87 ± 292.81

306.76 ± 634.82

297.62 ± 555.56

 rs2427837

G/G

194.33 ± 226.68

P = 0.343; Pc = 0.514

300.01 ± 412.43

P = 0.937; Pc = 0.937

265.68 ± 362.08

P = 0.841; Pc = 0.972

 

G/A

226.68 ± 241.53

290.18 ± 558.77

267.13 ± 468.99

 

A/A

140.60 ± 118.43

328.59 ± 421.92

298.76 ± 384.97

 rs2251746

T/T

190.06 ± 226.53

P = 0.034; c = 0.102

298.66 ± 413.61

P = 0.915; Pc = 0.937

263.74 ± 368.07

P = 0.372; Pc = 0.837

 

T/C

238.70 ± 238.76

297.09 ± 554.46

276.18 ± 466.41

 

C/C

105.86 ± 113.70

302.71 ± 425.47

255.75 ± 376.03

FCER1B

 rs1441586

T/T

176.95 ± 174.85

P = 0.098; Pc = 0.221

267.91 ± 326.28

P = 0.344; Pc = 0.830

233.06 ± 280.70

P = 0.972; Pc = 0.972

 

T/C

236.85 ± 248.41

286.22 ± 399.42

272.75 ± 361.14

 

C/C

181.37 ± 252.96

374.63 ± 738.18

303.91 ± 616.37

 rs569108

A/A

210.43 ± 229.10

P = 0.006; Pc = 0.027

309.51 ± 487.16

P = 0.242; Pc = 0.830

275.40 ± 419.36

P = 0.114; Pc = 0.549

 

A/G

11.00 ± 4.58

175.38 ± 165.47

160.91 ± 164.89

 

G/G

–

–

–

 rs512555

C/C

210.43 ± 229.10

P = 0.006; Pc = 0.027

308.11 ± 485.44

P = 0.369; Pc = 0.830

274.67 ± 418.34

P = 0.183; Pc = 0.549

 

C/T

11.00 ± 4.58

182.70 ± 166.24

166.91 ± 166.18

 

T/T

–

–

–

FCER1G

 rs11587213

A/A

200.60 ± 231.02

P = 0.954; Pc = 0.954

310.60 ± 510.95

P = 0.737; Pc = 0.937

273.55 ± 440.24

P = 0.921; Pc = 0.972

 

A/G

224.68 ± 229.73

257.38 ± 307.77

249.42 ± 285.10

 

G/G

152.00 ± 80.61

380.17 ± 666.52

323.13 ± 573.94

 rs2070901

G/G

211.39 ± 219.17

P = 0.843; Pc = 0.954

299.32 ± 421.34

P = 0.834; Pc = 0.937

271.91 ± 370.55

P = 0.969; Pc = 0.972

 

G/T

187.57 ± 181.20

312.20 ± 576.70

267.26 ± 476.60

 

T/T

279.13 ± 489.95

247.19 ± 244.88

254.28 ± 307.33

 rs11421

T/T

201.13 ± 232.38

P = 0.918; Pc = 0.954

269.59 ± 464.41

P = 0.089; Pc = 0.801

274.04 ± 401.77

P = 0.163; Pc = 0.549

 

T/C

225.03 ± 232.90

338.47 ± 464.41

305.21 ± 421.82

 

C/C

143.67 ± 52.71

587.43 ± 471.60

430.36 ± 426.20

  1. P values correspond to Kruskal-Wallis tests for independent samples. Pc correspond values adjusted for multiple comparisons according the False Discovery Rate (FDR) procedure. K-W test: Kruskall-Wallis test.
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