Figure 3

SEM and TEM analysis of iPSC derived microvesicles.
SEM analysis of MV populations isolated from iPSCs revealed a heterogenous population of spheroid vesicles ranging in size from 30–300 nm. (A) SEM of an MV population with a sample microparticle measured with a diameter of 103 nM, scale bar: 200 nm. (B) A higher magnification SEM image showing measured exosomes with diameters of 73.60 and 93.42 nm. (C) TEM analysis of MVs isolated from iPSC supernatant showed characteristic cup-shaped morphology and size (arrowhead) and (D) spheroid exosome (arrowhead) scale bar: 100 nm.